Assay Detail

CHEMBL3389197

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Functional

Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Open DB target context

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NON-PROTEIN TARGET (CHEMBL3879801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	SK-OV-3
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Hybrids of phenylsulfonylfuroxan and coumarin as potent antitumor agents.

Liu MM, Chen XY, Huang YQ, Feng P, Guo YL, Yang G, Chen Y.
J Med Chem (2014) 57 : 9343 -9356
PubMed 25350923 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.08	7.08

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3358557	—	—	1	7.08

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3358557	—	IC50	=	83.0	nM	7.08