Assay Detail
ADMET
CHEMBL3389563
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Cytotoxicity against CHOK1 cells after 24 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO-K1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
6-Hydroxyquinolinium salts differing in the length of alkyl side-chain: synthesis and antimicrobial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.58 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2414246 | — | — | 1 | 4.82 |
| CHEMBL334255 | CETYLPYRIDINIUM BROMIDE | — | 1 | 4.77 |
| CHEMBL3338619 | — | — | 1 | 4.70 |
| CHEMBL112719 | — | — | 1 | 4.62 |
| CHEMBL3181920 | — | — | 1 | 4.60 |
| CHEMBL2355417 | — | — | 1 | 4.54 |
| CHEMBL3338618 | — | — | 1 | 4.50 |
| CHEMBL3338621 | — | — | 1 | 4.41 |
| CHEMBL3338617 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2414246 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL334255 | CETYLPYRIDINIUM BROMIDE | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL3338619 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL112719 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL3181920 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL2355417 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL3338618 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL3338621 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL3338617 | — | IC50 | = | 50000.0 | nM | 4.30 |