Assay Detail
Functional
CHEMBL3390168
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Inhibition of LPS and IFNgamma-induced nitric oxide production in mouse RAW264.7 cells incubated for 16 hrs by Griess assay
11
Total Activities
11
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Polyyne hybrid compounds from Notopterygium incisum with peroxisome proliferator-activated receptor gamma agonistic effects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 10 | - | - |
| IC50 | 1 | 4.84 | 4.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3358036 | — | — | 1 | 4.84 |
| CHEMBL3358033 | — | — | 1 | - |
| CHEMBL3358034 | — | — | 1 | - |
| CHEMBL3358035 | — | — | 1 | - |
| CHEMBL3358037 | — | — | 1 | - |
| CHEMBL3358038 | — | — | 1 | - |
| CHEMBL3358039 | — | — | 1 | - |
| CHEMBL3358040 | — | — | 1 | - |
| CHEMBL3358041 | — | — | 1 | - |
| CHEMBL3358042 | — | — | 1 | - |
| CHEMBL3358043 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3358036 | — | IC50 | = | 14600.0 | nM | 4.84 |
| CHEMBL3358033 | — | Inhibition | - | % | - | |
| CHEMBL3358034 | — | Inhibition | - | % | - | |
| CHEMBL3358035 | — | Inhibition | - | % | - | |
| CHEMBL3358037 | — | Inhibition | - | % | - | |
| CHEMBL3358038 | — | Inhibition | - | % | - | |
| CHEMBL3358039 | — | Inhibition | - | % | - | |
| CHEMBL3358040 | — | Inhibition | - | % | - | |
| CHEMBL3358041 | — | Inhibition | - | % | - | |
| CHEMBL3358042 | — | Inhibition | - | % | - | |
| CHEMBL3358043 | — | Inhibition | - | % | - |