Assay Detail
Binding
CHEMBL3390933
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of JMJD2A (unknown origin) using ARK(me3)STGGK peptide as substrate preincubated for 1 to 30 mins followed by substrate addition by MALDI-TOF/MS analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of second generation epigenetic agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.15 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL583959 | BIS(PYRROLIDINYLTHIOCARBONYL)DISULFIDE | — | 1 | 5.48 |
| CHEMBL3347572 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL583959 | BIS(PYRROLIDINYLTHIOCARBONYL)DISULFIDE | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL3347572 | — | IC50 | = | 15300.0 | nM | 4.82 |