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Assay Detail

CHEMBL3391163

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AmpC beta-lactamase (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Not specified
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications
Trippier PC, McGuigan C
Medchemcomm (2010) 1 : 183 -198
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 5 7.69 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL429972 1 9.00
CHEMBL257468 1 9.00
CHEMBL404155 1 7.46
CHEMBL617 CEPHALOTHIN 4.0 1 6.50
CHEMBL3347545 1 6.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL429972 Ki = 1.0 nM 9.00
CHEMBL257468 Ki = 1.0 nM 9.00
CHEMBL404155 Ki = 35.0 nM 7.46
CHEMBL617 CEPHALOTHIN Ki = 320.0 nM 6.50
CHEMBL3347545 Ki = 320.0 nM 6.50