Assay Detail
Binding
CHEMBL3391503
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Inhibition of SIRT-2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
NAD-dependent protein deacetylase sirtuin-2 (CHEMBL4462) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of second generation epigenetic agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.72 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224864 | — | — | 1 | 5.46 |
| CHEMBL3222141 | — | — | 1 | 4.81 |
| CHEMBL226115 | — | — | 1 | 4.46 |
| CHEMBL561194 | ANILINOBENZAMIDE | — | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224864 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL3222141 | — | IC50 | = | 15500.0 | nM | 4.81 |
| CHEMBL226115 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL561194 | ANILINOBENZAMIDE | IC50 | = | 74000.0 | nM | 4.13 |