Assay Detail
Binding
CHEMBL3391582
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-CP55940 from human cannabinoid CB2 receptor expressed in Sf9 insect cells after 70 mins by scintillation counting
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and structureactivity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 9.00 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | — | 1 | 9.50 |
| CHEMBL3347370 | — | — | 1 | 9.10 |
| CHEMBL3347369 | — | — | 1 | 8.80 |
| CHEMBL188 | WIN-552122 | — | 1 | 8.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL559612 | CP-55940 | Ki | = | 0.3162 | nM | 9.50 |
| CHEMBL3347370 | — | Ki | = | 0.7943 | nM | 9.10 |
| CHEMBL3347369 | — | Ki | = | 1.585 | nM | 8.80 |
| CHEMBL188 | WIN-552122 | Ki | = | 2.512 | nM | 8.60 |