Assay Detail
Binding
CHEMBL3395014
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse iNOS
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based design of bacterial nitric oxide synthase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.05 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1615292 | — | — | 1 | 5.47 |
| CHEMBL3128242 | — | — | 1 | 5.28 |
| CHEMBL2326360 | — | — | 1 | 5.20 |
| CHEMBL3394388 | — | — | 1 | 5.15 |
| CHEMBL3394387 | — | — | 1 | 4.89 |
| CHEMBL3394386 | — | — | 1 | 4.84 |
| CHEMBL2326358 | — | — | 1 | 4.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1615292 | — | Ki | = | 3400.0 | nM | 5.47 |
| CHEMBL3128242 | — | Ki | = | 5200.0 | nM | 5.28 |
| CHEMBL2326360 | — | Ki | = | 6310.0 | nM | 5.20 |
| CHEMBL3394388 | — | Ki | = | 7098.0 | nM | 5.15 |
| CHEMBL3394387 | — | Ki | = | 12750.0 | nM | 4.89 |
| CHEMBL3394386 | — | Ki | = | 14410.0 | nM | 4.84 |
| CHEMBL2326358 | — | Ki | = | 32500.0 | nM | 4.49 |