Assay Detail
Binding
CHEMBL3395145
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Plk2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase PLK2 (CHEMBL5938) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of indole-3-carboxylic acids as non-ATP-competitive Polo-like kinase 1 (Plk1) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.83 | 4.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672002 | THYMOQUINONE | 2.0 | 1 | 4.83 |
| CHEMBL3394764 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672002 | THYMOQUINONE | IC50 | = | 14720.0 | nM | 4.83 |
| CHEMBL3394764 | — | IC50 | > | 50000.0 | nM | - |