Assay Detail
Binding
CHEMBL3395162
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DPDPE from delta opioid receptor in CD1 mouse whole brain minus cerebellum membranes by liquid scintillation counting
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Methoxyflavones from Stachys glutinosa with binding affinity to opioid receptors: in silico, in vitro, and in vivo studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 5.14 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL556578 | MORPHINE HYDROCHLORIDE | 3.0 | 1 | 7.00 |
| CHEMBL476121 | XANTHOMICROL | — | 1 | 5.44 |
| CHEMBL73930 | TANGERETIN | — | 1 | 5.16 |
| CHEMBL312750 | EUPATILIN | -1.0 | 1 | 4.92 |
| CHEMBL312790 | SIDERITIFLAVONE | — | 1 | 4.90 |
| CHEMBL3394775 | — | — | 1 | 4.63 |
| CHEMBL3394774 | — | — | 1 | 4.60 |
| CHEMBL74272 | — | — | 1 | 4.43 |
| CHEMBL226512 | GARDENIN B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL556578 | MORPHINE HYDROCHLORIDE | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL476121 | XANTHOMICROL | Ki | = | 3600.0 | nM | 5.44 |
| CHEMBL73930 | TANGERETIN | Ki | = | 7000.0 | nM | 5.16 |
| CHEMBL312750 | EUPATILIN | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL312790 | SIDERITIFLAVONE | Ki | = | 12500.0 | nM | 4.90 |
| CHEMBL3394775 | — | Ki | = | 23500.0 | nM | 4.63 |
| CHEMBL3394774 | — | Ki | = | 25000.0 | nM | 4.60 |
| CHEMBL74272 | — | Ki | = | 37500.0 | nM | 4.43 |
| CHEMBL226512 | GARDENIN B | Ki | > | 50000.0 | nM | - |