Assay Detail
Functional
CHEMBL3396046
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Cytotoxicity against rat C6 cells assessed as reduction in cell viability at 0.1 to 5 uM after 24 hrs by MTT assay
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | C6 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 3 | - | - |
| IC50 | 1 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1649601 | — | — | 2 | 5.30 |
| CHEMBL3393790 | — | — | 1 | - |
| CHEMBL3393789 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1649601 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL3393790 | — | Activity | - | — | - | |
| CHEMBL3393789 | — | Activity | - | — | - | |
| CHEMBL1649601 | — | Activity | - | — | - |