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Assay Detail

CHEMBL3396593

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against mouse P388D1 HepG2 cells after 48 hrs by crystal violet staining method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type P388D1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Design, synthesis, and biological evaluation of aminothiazole derivatives against the fungal pathogens Histoplasma capsulatum and Cryptococcus neoformans.
Khalil A, Edwards JA, Rappleye CA, Tjarks W.
Bioorg Med Chem (2015) 23 : 532 -547
PubMed 25543205 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.27 4.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3394576 1 4.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3394576 IC50 = 54000.0 nM 4.27