Assay Detail
Binding
CHEMBL3396752
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Inhibition of JNK3 (unknown origin) after 1 hr incubation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of c-Jun N-terminal kinases: an update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.74 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3393608 | — | — | 1 | 9.30 |
| CHEMBL3393607 | — | — | 1 | 9.15 |
| CHEMBL2216824 | — | — | 1 | 9.00 |
| CHEMBL3393606 | — | — | 1 | 6.15 |
| CHEMBL3393605 | — | — | 1 | 5.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3393608 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL3393607 | — | IC50 | = | 0.7 | nM | 9.15 |
| CHEMBL2216824 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3393606 | — | IC50 | = | 709.0 | nM | 6.15 |
| CHEMBL3393605 | — | IC50 | = | 7750.0 | nM | 5.11 |