Assay Detail
Functional
CHEMBL3399598
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction of LPS-induced NO production
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive benzofuran derivatives: moracins A-Z in medicinal chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.85 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2018876 | MORACIN C | — | 1 | 5.10 |
| CHEMBL3397399 | — | — | 1 | 4.84 |
| CHEMBL463241 | MORACIN D | — | 1 | 4.75 |
| CHEMBL380456 | (+/-)-MORACIN P | — | 1 | 4.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2018876 | MORACIN C | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3397399 | — | IC50 | = | 14300.0 | nM | 4.84 |
| CHEMBL463241 | MORACIN D | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL380456 | (+/-)-MORACIN P | IC50 | = | 19300.0 | nM | 4.71 |