Assay Detail
Binding
CHEMBL3405398
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human FAAH using [ethanolamine 1-3H] substrate assessed as radioactivity by liquid scintillation counting analysis
6
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Loratadine analogues as MAGL inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.21 | 5.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3087181 | — | — | 2 | 5.32 |
| CHEMBL3402827 | — | — | 2 | 5.16 |
| CHEMBL3401455 | — | — | 2 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3087181 | — | IC50 | = | 4786.3 | nM | 5.32 |
| CHEMBL3087181 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL3402827 | — | IC50 | = | 6918.31 | nM | 5.16 |
| CHEMBL3402827 | — | IC50 | = | 6910.0 | nM | 5.16 |
| CHEMBL3401455 | — | IC50 | = | 7244.36 | nM | 5.14 |
| CHEMBL3401455 | — | IC50 | = | 7240.0 | nM | 5.14 |