Assay Detail
Binding
CHEMBL3406337
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK9/cyclin T1 (unknown origin) expressed in baculovirus infected Sf9 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel arylazopyrazole inhibitors of cyclin-dependent kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.29 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3402056 | — | — | 1 | 6.55 |
| CHEMBL215205 | — | — | 1 | 6.46 |
| CHEMBL3402060 | — | — | 1 | 5.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3402056 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL215205 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL3402060 | — | IC50 | = | 1350.0 | nM | 5.87 |