Assay Detail
ADMET
CHEMBL3406903
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Cytotoxicity against human GES-1 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | GES1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and synthesis of novel 1,2,3-triazole-pyrimidine-urea hybrids as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.43 | 4.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3401103 | — | — | 1 | 4.45 |
| CHEMBL3401109 | — | — | 1 | 4.41 |
| CHEMBL3401092 | — | — | 1 | - |
| CHEMBL3401099 | — | — | 1 | - |
| CHEMBL3401100 | — | — | 1 | - |
| CHEMBL3400159 | — | — | 1 | - |
| CHEMBL3401104 | — | — | 1 | - |
| CHEMBL3401110 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3401103 | — | IC50 | = | 35690.0 | nM | 4.45 |
| CHEMBL3401109 | — | IC50 | = | 38710.0 | nM | 4.41 |
| CHEMBL3401092 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL3401099 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL3401100 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL3400159 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL3401104 | — | IC50 | > | 64000.0 | nM | - |
| CHEMBL3401110 | — | IC50 | > | 64000.0 | nM | - |