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Assay Detail

CHEMBL3406941

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of human neutrophil migration incubated for 30 mins prior to fMLP challenge by boyden chamber assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Neutrophil
Confidence 1 — Organism
Curated By Autocuration

Target

Neutrophil (CHEMBL613710)
Type CELL-LINE

Publication

Cannabidiol (CBD) and its analogs: a review of their effects on inflammation.
Burstein S.
Bioorg Med Chem (2015) 23 : 1377 -1385
PubMed 25703248 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.42 9.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL190461 CANNABIDIOL 4.0 1 9.35
CHEMBL3402654 1 7.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL190461 CANNABIDIOL IC50 = 0.45 nM 9.35
CHEMBL3402654 IC50 = 33.0 nM 7.48