Assay Detail
Binding
CHEMBL3411698
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Inhibition of rat TSPO
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ether analogues of DPA-714 with subnanomolar affinity for the translocator protein (TSPO).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.84 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2068817 | — | — | 1 | 9.15 |
| CHEMBL481537 | PK-11195 | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2068817 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL481537 | PK-11195 | Ki | = | 3.0 | nM | 8.52 |