Translocator protein · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P16257. Use UniProt P16257 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16257 as the stable identity anchor, then attach disease evidence before program review.
Translocator protein
Review this target as Translocator protein, mapped to UniProt P16257. Sequence length is 169 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Translocator protein as ChEMBL target CHEMBL4552, mapped to UniProt P16257. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Translocator protein is the right protein anchor across sources, using UniProt P16257 as the stable mapping.
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| Preferred Name | Translocator protein |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P16257 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Translocator protein |
| UniProt Accession | P16257 |
| Component Type | Protein |
| Sequence Length | 169 aa |
Translocator protein
Review this target as Translocator protein, mapped to UniProt P16257. Sequence length is 169 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL63064 | 10.37 | Ki | 0.043 | Preclinical |
| CHEMBL2070800 | 10.3 | Ki | 0.05 | Preclinical |
| CHEMBL2070787 | 10.3 | Ki | 0.05 | Preclinical |
| CHEMBL5288131 | 10.15 | Ki | 0.07 | Preclinical |
| CHEMBL401000 | 10.14 | Ki | 0.0726 | Preclinical |
| CHEMBL205971 | 10.13 | Ki | 0.074 | Preclinical |
| CHEMBL292092 | 10.11 | Ki | 0.078 | Preclinical |
| CHEMBL253596 | 10.01 | Ki | 0.0978 | Preclinical |
| CHEMBL381602 | 10.01 | Ki | 0.098 | Preclinical |
| CHEMBL135514 | 10.0 | Ki | 0.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 59 | 212 | 7.6 |
| tissue-based format | 55 | 289 | 7.7 |
| cell membrane format | 41 | 416 | 7.8 |
| assay format | 24 | 136 | 7.7 |
| cell-based format | 15 | 34 | 7.7 |
| organism-based format | 6 | 26 | 7.3 |
| microsome format | 2 | 6 | 7.0 |
| mitochondrion format | 2 | 16 | 8.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 14 | 0 | — |
| organism-based format | 12 | 0 | — |
| assay format | 4 | 0 | — |
| mitochondrion format | 1 | 0 | — |