Assay Detail
Functional
CHEMBL3413293
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Cytotoxicity against human A253 cells assessed as cell survival after 96 hrs by SRB assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A253 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antitumor activity of ring A modified 11-keto-β-boswellic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.58 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3401910 | — | — | 1 | 5.25 |
| CHEMBL3409842 | — | — | 1 | 4.81 |
| CHEMBL237111 | AKBA | -1.0 | 1 | 4.77 |
| CHEMBL3409840 | — | — | 1 | 4.74 |
| CHEMBL3409846 | — | — | 1 | 4.42 |
| CHEMBL3409841 | — | — | 1 | 4.41 |
| CHEMBL3409844 | — | — | 1 | 4.40 |
| CHEMBL3409845 | — | — | 1 | 4.37 |
| CHEMBL437964 | 11-KETO BOSWELLIC ACID | — | 1 | 4.34 |
| CHEMBL3409843 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3401910 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL3409842 | — | IC50 | = | 15500.0 | nM | 4.81 |
| CHEMBL237111 | AKBA | IC50 | = | 16900.0 | nM | 4.77 |
| CHEMBL3409840 | — | IC50 | = | 18100.0 | nM | 4.74 |
| CHEMBL3409846 | — | IC50 | = | 38200.0 | nM | 4.42 |
| CHEMBL3409841 | — | IC50 | = | 39400.0 | nM | 4.41 |
| CHEMBL3409844 | — | IC50 | = | 40200.0 | nM | 4.40 |
| CHEMBL3409845 | — | IC50 | = | 42300.0 | nM | 4.37 |
| CHEMBL437964 | 11-KETO BOSWELLIC ACID | IC50 | = | 45900.0 | nM | 4.34 |
| CHEMBL3409843 | — | IC50 | = | 54900.0 | nM | 4.26 |