Assay Detail
Binding
CHEMBL3418982
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli FtsZ polymerization
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.16 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL293492 | CINNAMALDEHYDE | -1.0 | 1 | 5.16 |
| CHEMBL1240857 | VIRIDITOXIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL293492 | CINNAMALDEHYDE | IC50 | = | 6860.0 | nM | 5.16 |
| CHEMBL1240857 | VIRIDITOXIN | IC50 | = | 8.2 | ug.mL-1 | - |