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Assay Detail

CHEMBL3419202

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Escherichia coli FtsZ by fluorescence anisotrophy
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cell division protein FtsZ (CHEMBL3999)
Type SINGLE PROTEIN
Organism Escherichia coli K-12

Publication

Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ.
Li X, Ma S.
Eur J Med Chem (2015) 95 : 1 -15
PubMed 25791674 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.78 4.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL48217 DAPI 1 4.78

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL48217 DAPI Kd = 16600.0 nM 4.78