Assay Detail
Binding
CHEMBL3420873
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human mPGES1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Macrophage-expressed gene 1 protein (CHEMBL3414409) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.68 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL221137 | EMBELIN | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL221137 | EMBELIN | IC50 | = | 210.0 | nM | 6.68 |