Assay Detail
Functional
CHEMBL3423733
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human SGC7901 cells after 38 hrs by MTT assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SGC-7901 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel myricetin derivatives: Design, synthesis and anticancer activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 4.96 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.46 |
| CHEMBL3423397 | — | — | 1 | 5.24 |
| CHEMBL3423391 | — | — | 1 | 5.22 |
| CHEMBL3423393 | — | — | 1 | 5.16 |
| CHEMBL3423394 | — | — | 1 | 5.11 |
| CHEMBL3423399 | — | — | 1 | 5.06 |
| CHEMBL3423395 | — | — | 1 | 5.00 |
| CHEMBL3423398 | — | — | 1 | 4.99 |
| CHEMBL3423387 | — | — | 1 | 4.95 |
| CHEMBL3423392 | — | — | 1 | 4.90 |
| CHEMBL3423396 | — | — | 1 | 4.79 |
| CHEMBL3423386 | — | — | 1 | 4.78 |
| CHEMBL3423390 | — | — | 1 | 4.57 |
| CHEMBL3423384 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL3423397 | — | IC50 | = | 5720.0 | nM | 5.24 |
| CHEMBL3423391 | — | IC50 | = | 6080.0 | nM | 5.22 |
| CHEMBL3423393 | — | IC50 | = | 6950.0 | nM | 5.16 |
| CHEMBL3423394 | — | IC50 | = | 7720.0 | nM | 5.11 |
| CHEMBL3423399 | — | IC50 | = | 8730.0 | nM | 5.06 |
| CHEMBL3423395 | — | IC50 | = | 10110.0 | nM | 5.00 |
| CHEMBL3423398 | — | IC50 | = | 10250.0 | nM | 4.99 |
| CHEMBL3423387 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL3423392 | — | IC50 | = | 12510.0 | nM | 4.90 |
| CHEMBL3423396 | — | IC50 | = | 16220.0 | nM | 4.79 |
| CHEMBL3423386 | — | IC50 | = | 16510.0 | nM | 4.78 |
| CHEMBL3423390 | — | IC50 | = | 26750.0 | nM | 4.57 |
| CHEMBL3423384 | — | IC50 | = | 56850.0 | nM | 4.25 |