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Assay Detail

CHEMBL3427972

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against human CEM-SS cells assessed as cell growth inhibition
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type CEM-SS
Confidence 1 — Organism
Curated By Autocuration

Target

CEM-SS (CHEMBL614548)
Type CELL-LINE
Organism Homo sapiens

Publication

Sesquiterpenoid tropolone glycosides from Liriosma ovata.
Ma J, Pawar RS, Grundel E, Mazzola EP, Ridge CD, Masaoka T, Le Grice SF, Wilson J, Beutler JA, Krynitsky AJ.
J Nat Prod (2015) 78 : 315 -319
PubMed 25587934 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.93 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL550937 BETA-THUJAPLICINOL 1 5.64
CHEMBL853 ZALCITABINE 4.0 1 4.21
CHEMBL3426556 1 -
CHEMBL3426555 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL550937 BETA-THUJAPLICINOL IC50 = 2300.0 nM 5.64
CHEMBL853 ZALCITABINE IC50 = 61000.0 nM 4.21
CHEMBL3426556 IC50 > 50000.0 nM -
CHEMBL3426555 IC50 > 50000.0 nM -