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Assay Detail

CHEMBL3429347

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Binding
Activation of Staphylococcus aureus FtsZ GTPase activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cell division protein FtsZ (CHEMBL5096)
Type SINGLE PROTEIN
Organism Staphylococcus aureus

Publication

Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ.
Nepomuceno GM, Chan KM, Huynh V, Martin KS, Moore JT, O'Brien TE, Pollo LA, Sarabia FJ, Tadeus C, Yao Z, Anderson DE, Ames JB, Shaw JT.
ACS Med Chem Lett (2015) 6 : 308 -312
PubMed 25815151 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL511201 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL511201 EC50 = 4000.0 nM 5.40