Assay Detail
Functional
CHEMBL3429702
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Antirhinovirus activity in HRVM infected in H1-HeLa cells assessed as inhibition of virus-induced cytopathic effect after 3 days by Cell-Titer Glo viability assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human rhinovirus sp. |
| Cell Type | H1-HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 5.65 | 6.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3426598 | — | — | 1 | 6.06 |
| CHEMBL3426603 | — | — | 1 | 6.05 |
| CHEMBL3426601 | — | — | 1 | 5.99 |
| CHEMBL3426599 | — | — | 1 | 5.96 |
| CHEMBL3426597 | — | — | 1 | 5.86 |
| CHEMBL3426595 | — | — | 1 | 5.79 |
| CHEMBL2397317 | — | — | 1 | 5.60 |
| CHEMBL3426602 | — | — | 1 | 5.54 |
| CHEMBL3426594 | — | — | 1 | 5.54 |
| CHEMBL3426596 | — | — | 1 | 5.52 |
| CHEMBL236207 | BETA-2'-C-METHYL-7-DEAZA-ADENOSINE | — | 1 | 5.29 |
| CHEMBL3426600 | — | — | 1 | 4.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3426598 | — | EC50 | = | 880.0 | nM | 6.06 |
| CHEMBL3426603 | — | EC50 | = | 890.0 | nM | 6.05 |
| CHEMBL3426601 | — | EC50 | = | 1030.0 | nM | 5.99 |
| CHEMBL3426599 | — | EC50 | = | 1090.0 | nM | 5.96 |
| CHEMBL3426597 | — | EC50 | = | 1380.0 | nM | 5.86 |
| CHEMBL3426595 | — | EC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL2397317 | — | EC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL3426602 | — | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3426594 | — | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3426596 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL236207 | BETA-2'-C-METHYL-7-DEAZA-ADENOSINE | EC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL3426600 | — | EC50 | = | 24300.0 | nM | 4.61 |