Compound Detail
CHEMBL236207
BETA-2'-C-METHYL-7-DEAZA-ADENOSINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL236207 |
| Name | BETA-2'-C-METHYL-7-DEAZA-ADENOSINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IRZRJANZDIOOIF-GAJNKVMBSA-N |
10
Targets
54
Activities
2
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
280.3
MW (Da)
-0.98
ALogP
8
HBA
4
HBD
126.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 48 meas. best 7.35
IC50 6 meas. best 7.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| dengue virus type 2 CHEMBL613966 | EC50 | 7.35 | 4.921 | 45.0 | 10 |
| Unchecked CHEMBL612545 | IC50 | 7.16 | 6.3867 | 70.0 | 3 |
| Hepatitis C virus CHEMBL379 | EC50 | 7.1 | 6.6978 | 80.0 | 9 |
| Nucleic Acid CHEMBL345 | EC50 | 6.6 | 6.6 | 250.0 | 1 |
| Hepatitis C virus CHEMBL379 | IC50 | 6.52 | 6.52 | 300.0 | 1 |
| Zika virus CHEMBL4296612 | EC50 | 5.86 | 5.1748 | 1391.0 | 23 |
| West Nile virus CHEMBL613730 | EC50 | 5.35 | 5.35 | 4500.0 | 1 |
| Tick-borne encephalitis virus CHEMBL4296604 | EC50 | 5.29 | 5.29 | 5100.0 | 1 |
| Human rhinovirus sp. CHEMBL612470 | EC50 | 5.29 | 5.29 | 5100.0 | 1 |
| Dengue virus CHEMBL613757 | EC50 | 4.82 | 4.82 | 15000.0 | 2 |
| Yellow fever virus CHEMBL613731 | IC50 | 4.79 | 4.79 | 16300.0 | 1 |
| Zika virus CHEMBL4296612 | IC50 | 4.7 | 4.7 | 20000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine