Assay Detail
Binding
CHEMBL3430144
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Inhibition of Trypanosoma brucei FPPS
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma brucei |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.88 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL55140 | — | — | 1 | 6.64 |
| CHEMBL923 | RISEDRONIC ACID | 4.0 | 1 | 6.52 |
| CHEMBL293522 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL55140 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL923 | RISEDRONIC ACID | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL293522 | — | IC50 | = | 33000.0 | nM | 4.48 |