Assay Detail
Binding
CHEMBL3430146
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human FPPS in absence of pre-incubation of compound with enzyme
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.77 | 7.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL923 | RISEDRONIC ACID | 4.0 | 1 | 7.09 |
| CHEMBL293522 | — | — | 1 | 6.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL923 | RISEDRONIC ACID | IC50 | = | 82.0 | nM | 7.09 |
| CHEMBL293522 | — | IC50 | = | 363.0 | nM | 6.44 |