Assay Detail
ADMET
CHEMBL3540626
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Binding affinity to C-terminal His4-tagged CYP2B4 dH/H226Y mutant (unknown origin) after 2 hrs by isothermal titration calorimetric analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3527102 | — | — | 1 | 6.52 |
| CHEMBL275066 | — | — | 1 | 6.52 |
| CHEMBL14145 | — | — | 1 | 6.52 |
| CHEMBL14192 | BENZYLIMIDAZOLE | — | 1 | 6.52 |
| CHEMBL1229718 | — | — | 1 | 6.52 |
| CHEMBL1231913 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3527102 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL275066 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL14145 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL14192 | BENZYLIMIDAZOLE | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL1229718 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL1231913 | — | Kd | = | 300.0 | nM | 6.52 |