Assay Detail
Binding
CHEMBL3580146
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of factor10a (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa) from Natural Product Anabaenopeptin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.42 | 4.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL175436 | ANABAENOPEPTIN F | — | 1 | 4.42 |
| CHEMBL446236 | OSCILLAMIDE Y | — | 1 | - |
| CHEMBL3577334 | — | — | 1 | - |
| CHEMBL368684 | ANABAENOPEPTIN B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL175436 | ANABAENOPEPTIN F | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL446236 | OSCILLAMIDE Y | IC50 | - | — | - | |
| CHEMBL3577334 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL368684 | ANABAENOPEPTIN B | IC50 | > | 100000.0 | nM | - |