Assay Detail
Functional
CHEMBL3580280
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Potentiation of caspofungin-induced antifungal activity against Aspergillus fumigatus ATCC 46645 assessed as caspofungin IC50 at 2 ug/ml after 24 hrs by checkerboard method (Rvb = 33 nM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Aspergillus fumigatus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cyclic colisporifungin and linear cavinafungins, antifungal lipopeptides isolated from Colispora cavincola.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.21 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3577069 | — | — | 1 | 8.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3577069 | — | IC50 | = | 6.2 | nM | 8.21 |