Assay Detail
Binding
CHEMBL3582655
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Neristatin 1 provides critical insight into bryostatin 1 structure-function relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.28 | 9.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL449158 | BRYOSTATIN 1 | 2.0 | 1 | 9.32 |
| CHEMBL3581528 | — | — | 1 | 7.86 |
| CHEMBL3581527 | — | — | 1 | 7.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL449158 | BRYOSTATIN 1 | Ki | = | 0.48 | nM | 9.32 |
| CHEMBL3581528 | — | Ki | = | 13.8 | nM | 7.86 |
| CHEMBL3581527 | — | Ki | = | 21.2 | nM | 7.67 |