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Assay Detail

CHEMBL3582656

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human Toledo cells after 72 hrs by particle counter based cell counting assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Toledo
Confidence 1 — Organism
Curated By Autocuration

Publication

Neristatin 1 provides critical insight into bryostatin 1 structure-function relationships.
Kedei N, Kraft MB, Keck GE, Herald CL, Melody N, Pettit GR, Blumberg PM.
J Nat Prod (2015) 78 : 896 -900
PubMed 25808573 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.80 8.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3581527 1 8.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3581527 IC50 = 1.58 nM 8.80