Assay Detail
Functional
CHEMBL3582755
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Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition after 9 days by Whole cell growth assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycobacterium tuberculosis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 3.56 | 3.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3581506 | — | — | 1 | 3.60 |
| CHEMBL1770734 | — | — | 1 | 3.60 |
| CHEMBL344115 | — | — | 1 | 3.47 |
| CHEMBL3581507 | — | — | 1 | - |
| CHEMBL3581508 | — | — | 1 | - |
| CHEMBL3581510 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3581506 | — | IC50 | = | 249300.0 | nM | 3.60 |
| CHEMBL1770734 | — | IC50 | = | 250500.0 | nM | 3.60 |
| CHEMBL344115 | — | IC50 | = | 339800.0 | nM | 3.47 |
| CHEMBL3581507 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL3581508 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL3581510 | — | IC50 | > | 1000000.0 | nM | - |