Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3584024

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human GBM6 cells assessed as cell viability after 48 hrs by Alamar Blue assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type GBM6
Confidence 1 — Organism
Curated By Autocuration

Publication

Parthenolide prodrug LC-1 slows growth of intracranial glioma.
Hexum JK, Becker CM, Kempema AM, Ohlfest JR, Largaespada DA, Harki DA.
Bioorg Med Chem Lett (2015) 25 : 2493 -2495
PubMed 25978958 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.47 5.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4298697 1 5.47
CHEMBL3582134 1 5.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4298697 IC50 = 3400.0 nM 5.47
CHEMBL3582134 IC50 = 3500.0 nM 5.46