Assay Detail
Functional
CHEMBL3587219
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Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation rate after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of thiabendazole derivatives as anti-angiogenesis and vascular disrupting agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.99 | 6.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3585866 | — | — | 1 | 6.37 |
| CHEMBL199461 | — | — | 1 | 5.61 |
| CHEMBL306226 | BENZIMIDAZOLE | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3585866 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL199461 | — | IC50 | = | 2460.0 | nM | 5.61 |
| CHEMBL306226 | BENZIMIDAZOLE | IC50 | > | 100000.0 | nM | - |