Assay Detail
Functional
CHEMBL3588095
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human T24 cells harboring HRAS mutant assessed as reduction of metabolic activity after 72 hrs by resazurin assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T-24 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Potent Apoptotic Response Induced by Chloroacetamidine Anthrathiophenediones in Bladder Cancer Cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.26 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3586304 | — | — | 1 | 5.57 |
| CHEMBL3586305 | — | — | 1 | 5.54 |
| CHEMBL3586306 | — | — | 1 | 5.52 |
| CHEMBL472033 | — | — | 1 | 5.36 |
| CHEMBL3586307 | — | — | 1 | 5.17 |
| CHEMBL3586308 | — | — | 1 | 4.94 |
| CHEMBL2349420 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3586304 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL3586305 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3586306 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL472033 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL3586307 | — | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL3586308 | — | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL2349420 | — | IC50 | = | 19100.0 | nM | 4.72 |