Assay Detail
Functional
CHEMBL3588708
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Cytotoxicity against human LNCAP cells assessed as inhibition of cell proliferation by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Initial development of a cytotoxic amino-seco-CBI warhead for delivery by prodrug systems.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.21 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314487 | — | — | 1 | 7.75 |
| CHEMBL3586001 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314487 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL3586001 | — | IC50 | = | 218.0 | nM | 6.66 |