Assay Detail
Binding
CHEMBL3591374
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to ATAD2 (unknown origin) by BROMOscan panel based assay
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
ATPase family AAA domain-containing protein 2 (CHEMBL2150837) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3590408 | — | — | 2 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3590408 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL3590408 | — | Ki | = | 20.0 | nM | 7.70 |