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Assay Detail

CHEMBL3591382

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to CECR2 (unknown origin) by BROMOscan panel based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Chromatin remodeling regulator CECR2 (CHEMBL3108639)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.
Bamborough P, Chung CW, Furze RC, Grandi P, Michon AM, Sheppard RJ, Barnett H, Diallo H, Dixon DP, Douault C, Jones EJ, Karamshi B, Mitchell DJ, Prinjha RK, Rau C, Watson RJ, Werner T, Demont EH.
J Med Chem (2015) 58 : 6151 -6178
PubMed 26230603 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.10 6.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3590408 1 6.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3590408 Ki = 794.33 nM 6.10