Assay Detail
Binding
CHEMBL3591401
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to TAF1 in human HUT78 cells incubated for 45 mins by mass spectrometry based bromosphere chemoproteomic assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HuT78 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transcription initiation factor TFIID subunit 1 (CHEMBL3217390) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.40 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3590408 | — | — | 1 | 5.90 |
| CHEMBL3590405 | — | — | 1 | 5.80 |
| CHEMBL3590389 | — | — | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3590408 | — | Kd | = | 1258.93 | nM | 5.90 |
| CHEMBL3590405 | — | Kd | = | 1584.89 | nM | 5.80 |
| CHEMBL3590389 | — | Kd | = | 31622.78 | nM | 4.50 |