Assay Detail
Binding
CHEMBL3592008
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]methyltrienolone from androgen receptor in human prostate cancer cells
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Cancer cell lines |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A full conformational characterization of antiandrogen cortexolone-17-propionate and related compounds through theoretical calculations and nuclear magnetic resonance spectroscopy
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.30 | 7.30 |
| Ki | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3590187 | CLASCOTERONE | 4.0 | 2 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3590187 | CLASCOTERONE | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL3590187 | CLASCOTERONE | IC50 | = | 50.0 | nM | 7.30 |