Assay Detail
Functional
CHEMBL3592117
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Cytotoxicity against human HCT15 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-15 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.89 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.96 |
| CHEMBL444478 | ACETOSIDE | 2.0 | 1 | 5.56 |
| CHEMBL3359821 | — | — | 1 | 5.15 |
| CHEMBL3590257 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 109.0 | nM | 6.96 |
| CHEMBL444478 | ACETOSIDE | IC50 | = | 2730.0 | nM | 5.56 |
| CHEMBL3359821 | — | IC50 | = | 7030.0 | nM | 5.15 |
| CHEMBL3590257 | — | IC50 | > | 30000.0 | nM | - |