Assay Detail

CHEMBL3592956

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Functional

Antiviral activity against HIV1 assessed as inhibition of viral replication in cell based assay

ChEMBL ↗

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Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

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Primary target Human immunodeficiency virus 1

CHEMBL378

Anchored from Assay target.

Protein identity Human immunodeficiency virus 1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus 1
Confidence	1 — Organism
Curated By	Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus 1

Publication

The biology and synthesis of α-hydroxytropolones.

Meck C, D'Erasmo MP, Hirsch DR, Murelli RP.
Medchemcomm (2014) 5 : 842 -852
PubMed 25089179 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.52	6.52

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL135189	—	—	1	6.52

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL135189	—	IC50	=	300.0	nM	6.52