Assay Detail
Binding
CHEMBL3593060
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Inhibition of dopamine beta-oxygenase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The biology and synthesis of α-hydroxytropolones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.64 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3357560 | — | — | 1 | 5.70 |
| CHEMBL121188 | TROPOLONE | — | 1 | 5.70 |
| CHEMBL135189 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3357560 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL121188 | TROPOLONE | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL135189 | — | IC50 | = | 3000.0 | nM | 5.52 |