Assay Detail
ADMET
CHEMBL3595966
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Cytotoxicity against human WI-26 VA4 cells after 48 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-26 VA4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
γ-Benzylidene digoxin derivatives synthesis and molecular modeling: Evaluation of anticancer and the Na,K-ATPase activity effect.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.71 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3856118 | — | — | 1 | 6.19 |
| CHEMBL3594277 | — | — | 1 | 4.81 |
| CHEMBL3594281 | — | — | 1 | 4.54 |
| CHEMBL3594280 | — | — | 1 | 4.36 |
| CHEMBL3594278 | — | — | 1 | 4.27 |
| CHEMBL3594276 | — | — | 1 | 4.11 |
| CHEMBL1751 | DIGOXIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3856118 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL3594277 | — | IC50 | = | 15500.0 | nM | 4.81 |
| CHEMBL3594281 | — | IC50 | = | 28700.0 | nM | 4.54 |
| CHEMBL3594280 | — | IC50 | = | 44100.0 | nM | 4.36 |
| CHEMBL3594278 | — | IC50 | = | 54100.0 | nM | 4.27 |
| CHEMBL3594276 | — | IC50 | = | 78300.0 | nM | 4.11 |
| CHEMBL1751 | DIGOXIN | IC50 | - | — | - |