Assay Detail
Binding
CHEMBL3598440
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ST3Gal 1 (unknown origin)
7
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (CHEMBL3596074) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.15 | 6.06 |
| Ki | 1 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3596261 | — | — | 1 | 6.06 |
| CHEMBL3596260 | — | — | 2 | 5.66 |
| CHEMBL1170899 | — | — | 1 | 5.17 |
| CHEMBL1478 | LITHOCHOLIC ACID | — | 1 | 4.68 |
| CHEMBL1170697 | — | — | 1 | 4.52 |
| CHEMBL3596263 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3596261 | — | IC50 | = | 880.0 | nM | 6.06 |
| CHEMBL3596260 | — | Ki | = | 2200.0 | nM | 5.66 |
| CHEMBL3596260 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1170899 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL1478 | LITHOCHOLIC ACID | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL1170697 | — | IC50 | = | 30200.0 | nM | 4.52 |
| CHEMBL3596263 | — | IC50 | = | 168400.0 | nM | - |